"S100A4; engineered heart tissue; fibrosis; hypertrophic cardiomyopathy; ubiquitin proteasome system"

S100A4 as a target of the E3-ligase Asb2β and its effect on engineered heart tissue

Background: S100A4 has recently emerged as an important player in cardiac disease, affecting phenotype development in animal models of myocardial infarction and pathological cardiac hypertrophy, albeit it is unclear whether S100A4 exerts a …