"cardiac hypertrophy; cardiovascular; co-expression networks; transcription/RNA-seq; translation/Ribo-seq"

A multi-network comparative analysis of transcriptome and translatome identifies novel hub genes in cardiac remodeling

Our understanding of the transition from physiological to pathological cardiac hypertrophy remains elusive and largely based on reductionist hypotheses. Here, we profiled the translatomes of 15 mouse hearts to provide a molecular blueprint of altered …