"Calcium; Cardiomyopathy; Gene therapy; Heart failure; Junctophilin; T-tubule"

BACKGROUND: Junctophilin-2 (JPH2) is the primary structural protein for the coupling of transverse (T)-tubule associated cardiac L-type Ca channels and type-2 ryanodine receptors on the sarcoplasmic reticulum within junctional membrane complexes …